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Elemental Analysis :ICP OES

(Inductively Coupled Plasma Optical Emission Spectrometry)

Increasingly, ICP-MS and ICP-OES methods of analysis are being used to quantify the concentration of elements contained in pharmaceutical compounds. Validation of methods for quantification of elements in biological matrices such as whole blood, serum, plasma, cerebrospinal fluid, urine, milk, bone, homogenized organs and tissues may be performed following GLP predicate rules and bio analytical guidance. Veeda has experience in carrying out studies for different elements in different types of biological matrices

Few Examples

  • Platinum (Pt) is a component of cisplatin, carboplatin and oxiplatin: all used for oncology treatments
  • Iron (Fe) from Iron Sucrose, Ferumoxytol, Ferric Carboxymaltose, Sodium Ferric Gluconate and Iron Dextran
  • Lithium (Li) Carbonate indicated in the treatment of manic episodes of manic-depressive illness.
  • Potassium (K) chloride For the treatment of patients with hypokalemia.
  • Magnesium (Mg) glycerophosphate is given to supplement magnesium levels when the level of magnesium in the body is too low for the patients with chronic magnesium loss or hypomagnesaemia


Veeda has hands on experience of conducting studies on elements like Lithium , Potassium, Magnesium and iron Sucrose  with a very good ISR  pass percentage . The team has now experience in handling various molecules and the results generated are as per the CFR compliant which is done by adding strong IT controls for the data integrity part .the results are generated through Watson LIMS and then exported to Stats for further processing
Analyte Name No. of Study Perform Matrix Used ISR Percentage
Lithium (Li) 3 Human Plasma 98.50%
Potassium (K) 10 Human Urine 96.40%
Magnesium (Mg) 1 Human Serum 92.68%
Iron (Fe) for Iron Sucrose 4 Human Serum 91.73%
Iron (Fe) Sodium Ferric Gluconate 1 Dog Serum 99.20%
Iron (Fe) Ferric Carboxymaltose 1 Dog Serum 88.72%
Iron (Fe) Iron Dextran 1 Dog Serum 74.80%

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