In India we have a
large unit with a mixture of monitored (12)
and un-monitored beds (116). This unit served
the dual purpose of being one of the first
formal and fully equipped Phase I Units
in India but is also a large unit to accomplish
simple PK studies of bioavailability and
bioequivalence in large populations in a
short time. The unit is served by the bioanalytical
group who are on the same site. This group,
lead by John Allinson can provide method
development/validation and assays of most
pharmaceutical compounds using primarily
the LC/MS/MS with a variety of detection
and preparation methods. The workhorse of
the unit is the SCIEX4000 for novel molecules
and the difficult-to-measure compounds and
the SCIEX 3000 and 2000 for easily assayed
molecules. We also have HPLC facilities. |
